Welcome to the van den Akker Lab!

Structural Biology on Drug Target Proteins


The overall goal of my research is to elucidate the molecular intricacies of enzyme mechanism and receptor activation. Our projects range from guanylyl cyclases (blood pressure, vision, and bone growth) to beta-lactamases, penicillin binding proteins and other proteins related to antibiotic resistance. Our lab employs state of the art multi-disciplinary biophysical, biochemical, crystallographic, molecular biology, computational, and cell biology techniques.
Postdoc position available in the van den Akker lab; contact focco.vandenakker@case.edu